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(781) 474-3515

The Waltham office will be closing its doors on 

June 30th! 

So sad to say goodbye to Boston, but so happy to say Hello to Sarasota, Florida! 

Platelet Rich Plasma (PRP)

Platelet Rich Plasma (PRP)

1) What is PRP?

PRP is a Platelet Rich Plasma derived from your own blood. PRP is often referred to as “liquid gold” as it contains seven growth factors and nutrient-rich proteins essential for healing process. PRP stimulates growth of new healthy cells where there is an injury, thus accelerating the healing process by growing new healthy cells.

2) What is PRP used for?

PRP has been used for years to treat acute injuries, heal postsurgical repairs, arthritis, and slow to heal wounds. Famous athletes like Tiger Woods and tennis star Rafael Nadal have been known to use these injections to help heal injuries.


Now PRP has entered the field of aesthetics to promote skin rejuvenation and skin health. In cosmetics, PRP is used to rejuvenate and heal the skin on the face, neck and décolletage. It treats areas that are too risky for treatment with fillers, e.g. temples, area around the eyes and nasolabial folds. PRP treats wrinkles, acne scars, sun spots and other skin unevenness and discoloration. PRP improves general appearance of the skin and gives it a youthful glow and rejuvenated look.


Another exciting area where PRP is proven to be effective is treatment of hair thinning and hair loss. PRP treatment has shown significant decrease in hair loss and increase in hair growth in patients with androgenic alopecia who did not respond to the treatment with Monoxidil and Finasteride. In one of the research study “a significant reduction in hair loss was observed” and the study concluded that “PRP injection is a simple, cost effective and feasible treatment option for androgenic alopecia, with high overall patient satisfaction.” (Swapna et al, 2014).


Another randomized placebo controlled study revealed clinical improvement in the mean number of hairs at the end of the 3 treatment cycles, “with a mean increase of 33.6 hairs in the target area and a mean increase in total hair density of 45.9 hairs per cm2 compared with baseline values. No side effects were noted during treatment. The data clearly highlight the positive effects of PRP injections on male pattern hair loss and absence of major side effects.”


Click on the articles below to read the full study!

References:

Swapna S Khatu, Yuvraj E More, Neeta R Gokhale, Dipali C Chavhan, and Nitin Bendsure. 2014 Apr-Jun. “Platelet-Rich Plasma in Androgenic Alopecia: Myth or an Effective Tool”.J Cutan Aesthet Surg; 7(2): 107–110. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134641/

doi: 10.4103/0974-2077.138352

Pietro Gentile, a,b Simone Garcovich,c Alessandra Bielli,d Maria Giovanna Scioli,d Augusto Orlandi,d and Valerio Cervell. 2015 Nov. “The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial”. (11): 1317–1323. Stem Cells Transl Med. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622412/

doi: 10.5966/sctm.2015-0107

3) What does PRP do when used for cosmetic purposes

Platelet Rich Plasma (PRP) activates only when there is an injury. Therefore, microneedling or injecting is necessary for PRP to start working. PRP renews the skin by stimulating the growth of new healthy cells in place of the damaged cells. The skin becomes smoother, brighter, younger looking, pores become smaller. PRP can fill the areas under the eyes to improve the undereye hollowness that comes with age, and injecting PRP is safe compared to injecting fillers in this area. The results are best seen after 2-3 weeks and last for at least several months as new cells
are formed.

4) How is PRP prepared



● A healthcare professional will draw a sample of your blood. The amount of the sample depends on where the PRP will be injected, commonly between 10 and 20 milliliters. This is slightly larger than one teaspoon.


● The blood is placed into a centrifuge. This is a machine that spins around very quickly, causing the blood components to separate. The separation process takes about 15 minutes.


●  The separated plasma then is prepared for injection into the treatment area.


● The area is numbed with topical Lidocaine to make procedure easily tolerated


● PRP is injected into the areas that are difficult to treat with other procedures, e.g. area around and under your eyes, nasolabial folds, acne scars, etc. to help with sunken skin and volume loss.


● PRP can be pushed deep into the dermis using collagen induction device for all over rejuvenation of the face, neck and décolletage areas.

5) What to expect after the procedure?

Immediately after PRP injection procedure, the areas injected might be puffy and pink flushed as the healing process activates, so it would be wise not to plan any life-changing events that day. The redness subsides after few hours, but the puffiness may stake 1-2 days to subside untill PRP is reabsorbed by the body. It is expected to have minor bruising at the injection sites, everyone is different though.

You can resume your daily activities next day. You can expect minor peeling in 2-3 days as new skin is formed and the old layer needs to come off. This would be a good time for a gentle exfoliation to reveal your new glowing skin. Your skin will look better every day after the peeling is complete.

6) What are the side effects of PRP

PRP therapy has been proven safe and effective. It carries almost no adverse effects since the patient will be using their own blood. In multiple studies patients showed virtually no side effects. PRP being autogenous (derived from your own cells), reduces the risks for an allergic reaction that can occur from injecting other medications, such as steroids or hyaluronic acid. There are minor risks that come from any injection itself, including:

      • pain at the injection site
        • bruising 
        • redness
    • swelling
    • infection

Contraindications for PRP

The procedure may NOT be suitable for you if you:

• Have a known history of clotting or bleeding disorders such as hemophilia.

• Are immune deficient or immune suppressed due to medical conditions or medications.

• Suffer from uncontrolled diabetes (high blood sugar).

• Take anticoagulant (blood thinner) therapies such as warfarin, heparin, or low dose aspirin.

• Suffer from an active skin infection, including bacterial, viral, or fungal infection.

• Suffer from an infection such as hepatitis or human immunodeficiency virus (HIV).

• Have or had eczema, psoriasis, vitiligo, or auto-immune disease.

• Have an active rash on the face.

• Have a current outbreak of cold sores (herpes).

• Are currently taking acne medication with the ingredient isotretinoin (Accutane) or have taken isotretinoin in the past 6 months.

• Have actinic (solar) keratoses, keloid scars (or a history of keloid scars), warts, , or birthmarks or moles in the treatment area.

• Have darker skin type, as there is a risk of darkening or lightening of the skin after the procedure. Some of the devices authorized for marketing by the FDA were not studied in subjects with darker skin types.

• Are tan or planning to be in the sun in the two weeks following the procedure.

• Suffer from a known malignancy or are undergoing or about to undergo treatments using chemotherapy, radiotherapy, or steroids.

• Are pregnant or breastfeeding.

• Are allergic to stainless steel or to topical or local anesthetics or have a history of contact dermatitis to these products